Ono Pharmaceutical Co., Ltd.

4528.T
Drug Manufacturers - General
2026/08/21 Updated
Market Cap: $7.3B (¥1.2T)
Stock Price: $15.61 (¥2,482)
Exchange Rate: 1 USD = ¥158.98

Stock Price Chart

2026/08/21 Updated
16.58
PER (Price Earnings Ratio)
vs Industry Avg: +7.0
1.35
PBR (Price to Book Ratio)
vs Industry Avg: +0.1
3.22%
Dividend Yield
vs Industry Avg: +0.27%

Price Trend

2026/08/21 Updated
Short-term
5-Day MA
+1.53%
Near-term
25-Day MA
+3.19%
Mid-term
75-Day MA
+4.28%
Long-term
200-Day MA
+7.59%

Price & Trading Details

2026/08/21 Updated

PRICE

Previous Close ¥2,460
Open ¥2,491
High ¥2,499
Low ¥2,470
Close ¥2,482

TRADING

Volume 1,548,800
Average Volume 1,664,242
Turnover ¥38億
Min. Purchase ¥248,150

Analyst Recommendations 12 analysts

Updated 2026/08/01
Strong Buy
0
Buy
1
1
Hold
8
8
Sell
2
2
Strong Sell
1
1
Target Price (Mean)
¥2,500
Hold
¥3,200
High
¥2,450
Median
¥1,900
Low
+15% vs Current Price
This information is based on market data from third-party data providers and is for reference only. Investment decisions are your own responsibility.

Earnings Calendar

Updated 2026/08/01

Recent Earnings

Date EPS Est. EPS Actual Surprise
2026/07/30 ¥35.66 ¥51.40 +44.2%
2026/05/07 ¥15.64 ¥1.74 -88.9%
2026/02/01 ¥48.74 ¥61.42 +26.0%
2025/10/29 ¥46.54 ¥47.71 +2.5%

Shareholder Composition

Updated 2026/08/01
13.2%
Insider Holdings
39.5%
Institutional
47.3%
Public Float
227
Institutional Holders
Insider Holdings 13.2%
Institutional 39.5%
Public Float 47.3%

Top Mutual Funds / ETFs

Updated 2026/08/01

Major Holders

Updated 2026/08/01
Fund Name Ownership Shares Change
VANGUARD STAR FUNDS-Vanguard Total International Stock Index Fund
1.15%
5.7M -0.24%
VANGUARD TAX-MANAGED FUNDS-Vanguard Developed Markets Index Fund
0.76%
3.8M +2.62%
Goldman Sachs TRT-Goldman Sachs Intl Small Cap Insights Fd.
0.74%
3.7M +79.68%
iShares Trust-iShares Core MSCI EAFE ETF
0.54%
2.7M +1.24%
BlackRock Funds-BlackRock Advantage International Fund
0.38%
1.9M +20.78%
Dimensional ETF Trust-Dimensional International Value ETF
0.32%
1.6M +8.34%
Institution Ownership Shares Change
Pacer Advisors, Inc.
0.04%
215.6K +4.09%

Dividend History

Updated 2026/08/23
-%
Dividend Yield
¥40
Annual Dividend
-50.0%
YoY Growth
27.0%
Payout Ratio
Year Dividend Change
2026 ¥40 -50.0%
2025 ¥80 0.0%
2024 ¥80 +3.9%
2023 ¥77 +26.2%
2022 ¥61 -

Financial Performance

2026/08/23 Updated

Revenue & Profit

Margins

Cash Flow

Financial Health

2022 2023 2024 2025
Income Statement
Revenue ¥361,361M ¥447,187M ¥502,672M ¥486,871M
Gross Profit ¥267,850M ¥337,124M ¥375,547M ¥338,921M
Operating Income ¥103,196M ¥141,963M ¥159,936M ¥59,748M
Pretax Income ¥105,899M ¥144,445M ¥163,963M ¥64,646M
Net Income ¥80,519M ¥112,723M ¥127,977M ¥50,047M
EPS ¥162.16 ¥230.79 ¥266.57 ¥106.41
Operating Margin 28.56% 31.75% 31.82% 12.27%
Balance Sheet
Total Assets ¥739,203M ¥882,437M ¥913,668M ¥1,064,046M
Total Equity ¥655,906M ¥741,869M ¥792,961M ¥782,451M
Total Liabilities ¥83,297M ¥140,568M ¥120,707M ¥281,595M
Cash ¥69,112M ¥96,135M ¥166,141M ¥204,567M
Interest-bearing Debt ¥8,802M ¥9,168M ¥8,862M ¥146,678M
Equity Ratio 88.73% 84.07% 86.79% 73.54%
D/E Ratio 0.01 0.01 0.01 0.19
Cash Flow
Operating CF ¥61,829M ¥159,610M ¥110,660M ¥82,459M
Investing CF ¥6,038M -¥100,259M ¥48,077M -¥136,785M
Financing CF -¥60,237M -¥32,484M -¥89,848M ¥94,299M
Free CF ¥49,552M ¥145,113M ¥89,831M ¥74,469M
Efficiency
ROE 12.28% 15.19% 16.14% 6.40%
ROA 10.89% 12.77% 14.01% 4.70%

Latest IR Information

Company Information

English Name Ono Pharmaceutical Co., Ltd.
Japanese Name 小野薬品工業(株)
Stock Code 4528.T (JPX)
Sector / Industry Healthcare / Drug Manufacturers - General
Employees 4,206

About

Ono Pharmaceutical Co., Ltd. produces, purchases, and sells pharmaceuticals and diagnostic reagents worldwide. It offers Opdivo intravenous infusion and Kyprolis intravenous injection for malignant tumors; Emend capsule intravenous injections for chemotherapy-induced nausea and vomiting; Demser capsules for the symptoms in patients with pheochromocytoma; Mektovi, Velexbru, and Braftovi capsules for malignant tumors; and ADLUMIZ tablets for cancer cachexia. The company also provides Glactiv tablets for type 2 diabetes; Forxiga tablets for diabetes, chronic heart failure, and chronic kidney disease; Onoact intravenous infusion for tachyarrhythmia; Opalmon tablets to treat peripheral circulatory disorder; Coralan for chronic heart failure; Orencia injections for rheumatoid arthritis; Rivastach patches for Alzheimer's disease; Ongentys tablets for Parkinson's disease; Parsabiv for the treatment of secondary hyperparathyroidism; Staybla tablets for overactive bladder; Onon capsules and Dry Syrups for bronchial asthma and allergic rhinitis; and Joyclu intra-articular injection for the improvement of joint function, as well as Recalbon tablets for osteoporosis. In addition, it develops products for hepatocellular and urothelial carcinoma; ovarian, bladder, prostate, pancreatic, gastric, esophageal, colorectal, thyroid, cell lung, and breast cancer; acute myeloid leukemia; solid tumors; myelodysplastic syndrome; melanoma; T-cell lymphoma; tachyarrhythmia; pemphigus; scleroderma; seizures; diabetic polyneuropathy; neurodegenerative diseases; autoimmune diseases; narcolepsy; and thrombosis. The company has collaborations with Adimab LLC; Turbine Ltd.; Harvard University; Sibylla Biotech; and Congruence Therapeutics. Ono Pharmaceutical Co., Ltd. was founded in 1717 and is headquartered in Osaka, Japan.

Data provided by Yahoo Finance