Ono Pharmaceutical Co., Ltd.

4528.T
Drug Manufacturers - General
2026/10/08 12:11 Updated
Market Cap: $6.7B (¥1.1T)
Stock Price: $14.20 (¥2,243)
Exchange Rate: 1 USD = ¥157.98

Stock Price Chart

2026/10/08 12:11 Updated
15.19
PER (Price Earnings Ratio)
vs Industry Avg: +5.6
1.22
PBR (Price to Book Ratio)
vs Industry Avg: -0.1
3.52%
Dividend Yield
vs Industry Avg: +0.57%

Price Trend

2026/10/08 12:11 Updated
Short-term
5-Day MA
-1.13%
Near-term
25-Day MA
-4.13%
Mid-term
75-Day MA
-4.91%
Long-term
200-Day MA
-3.83%

Price & Trading Details

2026/10/08 12:11 Updated

PRICE

Previous Close ¥2,258
Open ¥2,281
High ¥2,281
Low ¥2,239
Close ¥2,243

TRADING

Volume 452,600
Average Volume 1,522,953
Turnover ¥10億
Min. Purchase ¥224,300

Analyst Recommendations 12 analysts

Updated 2026/10/01
Strong Buy
1
1
Buy
2
2
Hold
6
6
Sell
2
2
Strong Sell
1
1
Target Price (Mean)
¥2,508
Hold
¥3,200
High
¥2,450
Median
¥1,900
Low
+15% vs Current Price
This information is based on market data from third-party data providers and is for reference only. Investment decisions are your own responsibility.

Earnings Calendar

Updated 2026/10/01
OCT
29
2026
Next Earnings Release
Q4 FY2026
EPS Estimate: ¥46.54
20days

Recent Earnings

Date EPS Est. EPS Actual Surprise
2026/07/30 ¥35.66 ¥51.40 +44.2%
2026/05/07 ¥15.64 ¥1.74 -88.9%
2026/02/01 ¥48.74 ¥61.42 +26.0%
2025/10/29 ¥46.54 ¥47.71 +2.5%

Shareholder Composition

Updated 2026/10/01
12.3%
Insider Holdings
40.7%
Institutional
47.0%
Public Float
235
Institutional Holders
Insider Holdings 12.3%
Institutional 40.7%
Public Float 47.0%

Top Mutual Funds / ETFs

Updated 2026/10/01

Major Holders

Updated 2026/10/01
Fund Name Ownership Shares Change
VANGUARD STAR FUNDS-Vanguard Total International Stock Index Fund
1.15%
5.7M -0.24%
VANGUARD TAX-MANAGED FUNDS-Vanguard Developed Markets Index Fund
0.78%
3.9M +2.31%
iShares Trust-iShares Core MSCI EAFE ETF
0.55%
2.8M +1.60%
BlackRock Funds-BlackRock Advantage International Fund
0.38%
1.9M +20.78%
Dimensional ETF Trust-Dimensional International Value ETF
0.36%
1.8M +12.71%
iShares Trust-iShares MSCI EAFE Small-Cap ETF
0.27%
1.4M -9.30%
Institution Ownership Shares Change
Pacer Advisors, Inc.
0.04%
215.6K +4.09%

Dividend History

Updated 2026/10/04
-%
Dividend Yield
¥80
Annual Dividend
0.0%
YoY Growth
53.9%
Payout Ratio
Year Dividend Change
2026 ¥80 0.0%
2025 ¥80 0.0%
2024 ¥80 +3.9%
2023 ¥77 +26.2%
2022 ¥61 -

Financial Performance

2026/10/04 Updated

Revenue & Profit

Margins

Cash Flow

Financial Health

2022 2023 2024 2025
Income Statement
Revenue ¥361,361M ¥447,187M ¥502,672M ¥486,871M
Gross Profit ¥267,850M ¥337,124M ¥375,547M ¥338,921M
Operating Income ¥103,196M ¥141,963M ¥159,936M ¥59,748M
Pretax Income ¥105,899M ¥144,445M ¥163,963M ¥64,646M
Net Income ¥80,519M ¥112,723M ¥127,977M ¥50,047M
EPS ¥162.16 ¥230.79 ¥266.57 ¥106.41
Operating Margin 28.56% 31.75% 31.82% 12.27%
Balance Sheet
Total Assets ¥739,203M ¥882,437M ¥913,668M ¥1,064,046M
Total Equity ¥655,906M ¥741,869M ¥792,961M ¥782,451M
Total Liabilities ¥83,297M ¥140,568M ¥120,707M ¥281,595M
Cash ¥69,112M ¥96,135M ¥166,141M ¥204,567M
Interest-bearing Debt ¥8,802M ¥9,168M ¥8,862M ¥146,678M
Equity Ratio 88.73% 84.07% 86.79% 73.54%
D/E Ratio 0.01 0.01 0.01 0.19
Cash Flow
Operating CF ¥61,829M ¥159,610M ¥110,660M ¥82,459M
Investing CF ¥6,038M -¥100,259M ¥48,077M -¥136,785M
Financing CF -¥60,237M -¥32,484M -¥89,848M ¥94,299M
Free CF ¥49,552M ¥145,113M ¥89,831M ¥74,469M
Efficiency
ROE 12.28% 15.19% 16.14% 6.40%
ROA 10.89% 12.77% 14.01% 4.70%

Latest IR Information

Company Information

English Name Ono Pharmaceutical Co., Ltd.
Japanese Name 小野薬品工業(株)
Stock Code 4528.T (JPX)
Sector / Industry Healthcare / Drug Manufacturers - General
Employees 4,206

About

Ono Pharmaceutical Co., Ltd. produces, purchases, and sells pharmaceuticals and diagnostic reagents worldwide. It offers Opdivo intravenous infusion and Kyprolis intravenous injection for malignant tumors; Emend capsule intravenous injections for chemotherapy-induced nausea and vomiting; Demser capsules for the symptoms in patients with pheochromocytoma; Mektovi, Velexbru, and Braftovi capsules for malignant tumors; and ADLUMIZ tablets for cancer cachexia. The company also provides Glactiv tablets for type 2 diabetes; Forxiga tablets for diabetes, chronic heart failure, and chronic kidney disease; Onoact intravenous infusion for tachyarrhythmia; Opalmon tablets to treat peripheral circulatory disorder; Coralan for chronic heart failure; Orencia injections for rheumatoid arthritis; Rivastach patches for Alzheimer's disease; Ongentys tablets for Parkinson's disease; Parsabiv for the treatment of secondary hyperparathyroidism; Staybla tablets for overactive bladder; Onon capsules and Dry Syrups for bronchial asthma and allergic rhinitis; and Joyclu intra-articular injection for the improvement of joint function, as well as Recalbon tablets for osteoporosis. In addition, it develops products for hepatocellular and urothelial carcinoma; ovarian, bladder, prostate, pancreatic, gastric, esophageal, colorectal, thyroid, cell lung, and breast cancer; acute myeloid leukemia; solid tumors; myelodysplastic syndrome; melanoma; T-cell lymphoma; tachyarrhythmia; pemphigus; scleroderma; seizures; diabetic polyneuropathy; neurodegenerative diseases; autoimmune diseases; narcolepsy; and thrombosis. The company has strategic collaboration with Adimab LLC; Turbine Ltd.; Harvard University; Sibylla Biotech; Congruence Therapeutics; and Aitia, Inc. for drug discovery of novel therapeutic targets for neurological diseases. Ono Pharmaceutical Co., Ltd. was founded in 1717 and is headquartered in Osaka, Japan.

Data provided by Yahoo Finance