Ono Pharmaceutical Co., Ltd.

4528.T
Drug Manufacturers - General
2026/03/02 Updated
Market Cap: $8.1B (¥1.3T)
Stock Price: $17.14 (¥2,675)
Exchange Rate: 1 USD = ¥156.01

Stock Price Chart

2026/03/02 Updated
23.87
PER (Price Earnings Ratio)
vs Industry Avg: +14.3
1.50
PBR (Price to Book Ratio)
vs Industry Avg: +0.2
2.99%
Dividend Yield
vs Industry Avg: +0.04%

Price Trend

2026/03/02 Updated
Short-term
5-Day MA
+1.39%
Near-term
25-Day MA
+8.29%
Mid-term
75-Day MA
+18.66%
Long-term
200-Day MA
+43.62%

Price & Trading Details

2026/03/02 Updated

PRICE

Previous Close ¥2,624
Open ¥2,600
High ¥2,675
Low ¥2,587
Close ¥2,675

TRADING

Volume 2,503,900
Average Volume 1,925,824
Turnover ¥67億
Min. Purchase ¥267,450

Analyst Recommendations 11 analysts

Updated 2026/03/01
Strong Buy
0
Buy
0
Hold
7
7
Sell
2
2
Strong Sell
2
2
Target Price (Mean)
¥2,046
Hold
¥2,950
High
¥1,925
Median
¥1,500
Low
-6% vs Current Price
This information is based on market data from third-party data providers and is for reference only. Investment decisions are your own responsibility.

Shareholder Composition

Updated 2026/03/01
13.2%
Insider Holdings
43.1%
Institutional
43.7%
Public Float
232
Institutional Holders
Insider Holdings 13.2%
Institutional 43.1%
Public Float 43.7%

Top Mutual Funds / ETFs

Updated 2026/03/01

Major Holders

Updated 2026/03/01
Fund Name Ownership Shares Change
VANGUARD STAR FUNDS-Vanguard Total International Stock Index Fund
1.14%
5.7M +0.04%
SCHWAB STRATEGIC TRUST-Schwab International Dividend Equity ETF
1.01%
5.0M +7.96%
VANGUARD TAX-MANAGED FUNDS-Vanguard Developed Markets Index Fund
0.72%
3.6M +2.38%
iShares Trust-iShares Core MSCI EAFE ETF
0.51%
2.6M 0.00%
Dimensional ETF Trust-Dimensional International Value ETF
0.29%
1.4M +9.74%
iShares Trust-iShares MSCI EAFE Small-Cap ETF
0.28%
1.4M +0.51%
Institution Ownership Shares Change
Pacer Advisors, Inc.
0.04%
215.6K +4.09%

Dividend History

Updated 2026/03/01
-%
Dividend Yield
¥80
Annual Dividend
0.0%
YoY Growth
75.2%
Payout Ratio
Year Dividend Change
2025 ¥80 0.0%
2024 ¥80 +3.9%
2023 ¥77 +26.2%
2022 ¥61 +20.8%
2021 ¥51 -

Financial Performance

2026/03/01 Updated

Revenue & Profit

Margins

Cash Flow

Financial Health

2022 2023 2024 2025
Income Statement
Revenue ¥361,361M ¥447,187M ¥502,672M ¥486,871M
Gross Profit ¥267,850M ¥337,124M ¥375,547M ¥338,921M
Operating Income ¥103,196M ¥141,963M ¥159,936M ¥59,748M
Pretax Income ¥105,899M ¥144,445M ¥163,963M ¥64,646M
Net Income ¥80,519M ¥112,723M ¥127,977M ¥50,047M
EPS ¥162.16 ¥230.79 ¥266.57 ¥106.41
Operating Margin 28.56% 31.75% 31.82% 12.27%
Balance Sheet
Total Assets ¥739,203M ¥882,437M ¥913,668M ¥1,064,046M
Total Equity ¥655,906M ¥741,869M ¥792,961M ¥782,451M
Total Liabilities ¥83,297M ¥140,568M ¥120,707M ¥281,595M
Cash ¥69,112M ¥96,135M ¥166,141M ¥204,567M
Interest-bearing Debt ¥8,802M ¥9,168M ¥8,862M ¥146,678M
Equity Ratio 88.73% 84.07% 86.79% 73.54%
D/E Ratio 0.01 0.01 0.01 0.19
Cash Flow
Operating CF ¥61,829M ¥159,610M ¥110,660M ¥82,459M
Investing CF ¥6,038M -¥100,259M ¥48,077M -¥136,785M
Financing CF -¥60,237M -¥32,484M -¥89,848M ¥94,299M
Free CF ¥49,552M ¥145,113M ¥89,831M ¥74,469M
Efficiency
ROE 12.28% 15.19% 16.14% 6.40%
ROA 10.89% 12.77% 14.01% 4.70%

Company Information

English Name Ono Pharmaceutical Co., Ltd.
Japanese Name 小野薬品工業(株)
Stock Code 4528.T (JPX)
Sector / Industry Healthcare / Drug Manufacturers - General
Employees 4,287

About

Ono Pharmaceutical Co., Ltd. produces, purchases, and sells pharmaceuticals and diagnostic reagents worldwide. It offers Opdivo intravenous infusion and Kyprolis intravenous injection for malignant tumors; Emend capsule intravenous injections for chemotherapy-induced nausea and vomiting; Demser capsules for the symptoms in patients with pheochromocytoma; Mektovi, Velexbru, and Braftovi capsules for malignant tumors; and ADLUMIZ tablets for cancer cachexia. The company also provides Glactiv tablets for type 2 diabetes; Forxiga tablets for diabetes, chronic heart failure, and chronic kidney disease; Onoact intravenous infusion for tachyarrhythmia; Opalmon tablets to treat peripheral circulatory disorder; Coralan for chronic heart failure; Orencia injections for rheumatoid arthritis; Rivastach patches for Alzheimer's disease; Ongentys tablets for Parkinson's disease; Parsabiv for the treatment of secondary hyperparathyroidism; Staybla tablets for overactive bladder; Onon capsules and Dry Syrups for bronchial asthma and allergic rhinitis; and Joyclu intra-articular injection for the improvement of joint function, as well as Recalbon tablets for osteoporosis. In addition, it develops products for hepatocellular and urothelial carcinoma; ovarian, bladder, prostate, pancreatic, gastric, esophageal, colorectal, thyroid, cell lung, and breast cancer; acute myeloid leukemia; solid tumors; myelodysplastic syndrome; melanoma; T-cell lymphoma; tachyarrhythmia; pemphigus; scleroderma; seizures; diabetic polyneuropathy; neurodegenerative diseases; autoimmune diseases; narcolepsy; and thrombosis. The company has collaborations with Adimab LLC to discover novel antibody drugs; Turbine Ltd. to identify and validate novel oncology targets; Harvard University for validating novel therapeutic targets; and Sibylla Biotech for central nervous system disorders. Ono Pharmaceutical Co., Ltd. was founded in 1717 and is headquartered in Osaka, Japan.

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