{"id":62524,"date":"2026-06-09T15:42:16","date_gmt":"2026-06-09T06:42:16","guid":{"rendered":"https:\/\/japanir.jp\/en\/ir\/4591-20260609-01_wp_basic\/"},"modified":"2026-07-12T11:23:00","modified_gmt":"2026-07-12T02:23:00","slug":"4591-20260609-01_wp_basic","status":"publish","type":"ir_release","link":"https:\/\/japanir.jp\/en\/company\/company-4591\/ir\/4591-20260609-01_wp_basic\/","title":{"rendered":"Notice of Progress and Contract Extension for Collaborative Research with the University of 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Inc.","jir_importance":"\u2605\u2605\u2605\u2606\u2606","jir_publication_date":"2026-06-09","jir_source_link":"[Placeholder]","jir_short_summary":"Reported nonclinical evaluation results of aptamer targeting RBM-006 for ocular diseases. Confirmed potential for lowering intraocular pressure, inhibiting angiogenesis, and anti-inflammatory effects in relation to glaucoma and retinal diseases. Joint research period extended to March 2027 with no increase in costs. Expectation of expanded license opportunities and value enhancement of the pipeline in the future.","jir_summary":"### News Overview\nRibomic announces progress of joint research with the Department of Ophthalmology, University of Tokyo, reporting that nonclinical evaluation of aptamer drugs centered on RBM-006 shows significant pharmacological efficacy for ocular diseases. In particular, three key pharmacological actions\u2014reduction of intraocular pressure, inhibition of angiogenesis, and anti-inflammatory effects\u2014have been confirmed. This is expected to broaden applications across many ophthalmic disease areas and to increase future license opportunities. The joint research period has been extended to March 2027, with no increase in costs.\n\n### Impact and Outlook\nThis development is positioned as a significant advancement that enhances the pipeline value for the company\u2019s focus area of ophthalmic diseases in clinical development. Indications of cross-aptamer efficacy suggest opportunities for expansion into large markets such as glaucoma, age-related macular degeneration, and diabetic retinopathy, and expect expansion of license agreements and partnerships. There is no cost increase due to contractual changes; only the research period has been extended.","jir_financial_highlights":"Announcement item: Unknown","jir_category":"Partnerships & M&A","jir_hashtags":"#Ribomic, #RBM006, #Ophthalmology, #IR","jir_key_figures":"RBM-006: Efficacy confirmed in nonclinical models\nJoint research period extended: to March 2027\nNo increase in joint research costs","jir_meta_title":"\u3010Ribomic\u3011Progress of collaboration with University of Tokyo and extension of contract period | June 2026","jir_meta_description":"Ribomic announces progress of joint research with the University of Tokyo Ophthalmology Department and extension of the contract period. Nonclinical evaluation of RBM-006 shows suppression of intraocular pressure, inhibition of angiogenesis, and anti-inflammatory effects. Contract extension through March 2027 with no cost increase.","jir_og_title":"Ribomic Announces Progress of Collaboration with University of Tokyo and Extension of Period","jir_og_description":"Nonclinical evaluation of RBM-006 confirms suppression of intraocular pressure, inhibition of angiogenesis, and anti-inflammatory effects. Joint research period extended to March 2027 with no cost increase.","jir_og_image_url":"\/assets\/og\/company-general_ir.jpg","jir_chart_data_collection":"[]","ir_related_company":60242,"ir_release_date":"","ir_type":"","ir_is_new":false,"ir_document_url":"","jir_ir_type":"general_ir","footnotes":""},"sector":[],"importance":[],"class_list":["post-62524","ir_release","type-ir_release","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Notice of Progress and Contract Extension for Collaborative Research with the University of Tokyo - Japan IR<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/japanir.jp\/en\/company\/company-4591\/ir\/4591-20260609-01_wp_basic\/\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/japanir.jp\/en\/company\/company-4591\/ir\/4591-20260609-01_wp_basic\/\",\"url\":\"https:\/\/japanir.jp\/en\/company\/company-4591\/ir\/4591-20260609-01_wp_basic\/\",\"name\":\"Notice of Progress and Contract Extension for Collaborative Research with the University of Tokyo - 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